The renin-angiotensin-aldosterone system: approaches to cardiac and renal therapy.
نویسندگان
چکیده
The renin-angiotensin-aldosterone system (RAAS) plays a prominent role in the pathophysiology of cardiac and renal diseases. Aldosterone leads to local effects of vasoconstriction, sodium resorption, and possibly inflammation and fibrosis in several organs. Pharmacologic manipulation of the RAAS may involve renin inhibitors, angiotensin-converting enzyme inhibitors, angiotensin II–receptor blockers, and aldosterone antagonists.
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ورودعنوان ژورنال:
- Compendium
دوره 31 1 شماره
صفحات -
تاریخ انتشار 2009